Drug Name:Clobetasone Butyrate
Drug Class:Topical Corticosteroid
Mechanism of Action:
  • Binds to glucocorticoid receptors in the cytoplasm of sensitive cells
  • Modulates transcription of genes that control the inflammatory and immune response
Use:
  • Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Side Effects:
  • Burning
  • Itching
  • Irritation
  • Dryness
  • Folliculitis
  • Hypertrichosis
  • Acneiform eruptions
  • Hypopigmentation
  • Perioral dermatitis
  • Allergic contact dermatitis
  • Skin atrophy
Contraindications:
  • Hypersensitivity to clobetasone butyrate or any component of the preparation
  • Viral infections of the skin
  • Tuberculosis of the skin
  • Fungal infections of the skin
  • Bacterial infections of the skin
  • Parasitic infections of the skin
  • Perioral dermatitis
  • Rosacea
  • Acne vulgaris
  • Skin atrophy
  • Children under 1 year of age
Specialty:
  • Dermatology
  • Allergy and Immunology